Abdominal Aortic Dissection in a Patient With Autosomal Dominant Polycystic Kidney Disease After Starting Peritoneal Dialysis.

نویسندگان

  • Yingying He
  • Qin Wang
  • Meng Zhang
  • Bo Wang
  • Zuying Xiong
  • Qiong Luo
  • Song Wu
چکیده

Autosomal dominant polycystic kidney disease (ADPKD), one of the most common genetic disorders, is caused by mutations in the PKD1 or PKD2 gene. ADPKD primarily affects the kidneys, causing the development of multiple bilateral cysts that are characteristic of this condition. Besides renal abnormalities, other manifestations of ADPKD include hepatic, pancreatic, and splenic cysts, intracranial aneurysms, aortic aneurysms, and mitral valve prolapse. Reports of ADPKD-associated abdominal aortic dissections are not rare, but there have been no reports of an ADPKD patient developing intestinal obstruction and abdominal aortic dissection after initiating peritoneal dialysis. Herein, we present one such case.

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Thank the editor and reviewers for these precious comments concerning my manuscript entitled "Whole exome sequencing reveals a stop-gain mutation of PKD2 in an autosomal dominant polycystic kidney disease family complicated with aortic dissection" (MGTC-D-17-00066R1). These comments are all valuable and very helpful for revising and improving my paper, as well as the important guiding significa...

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عنوان ژورنال:
  • Urology case reports

دوره 2 4  شماره 

صفحات  -

تاریخ انتشار 2014